I'm admittedly behind on the game: Is the current strat literally "Open random chests till the last one/you die"? Is there no other strat going on? Because man I die a lot.
There is only one mimic so those are your odds. The strategy is to pick the chest that you think is the mimic, open every
other chest and then leave. There really aren't any choices or decisions you can make to affect the outcome other than clearing the board. That's how it goes with games of chance. Odds work for and against you at the same time. Is it lucky to be struck by lightning 3 times?
Someone goes into trove for the first time, opens a loud thud on the first chest and walks out with a Shamash Robe. He then proceeds to use his next orb, gets another first chest loud thud and this time exits to nothing in the loot pool but a job card from the center chest. Trove dropped him another Shamash Robe but he never saw it in the treasure pool because he already had one...